Lats2 deficiency protects the heart against myocardial infarction by reducing inflammation and inhibiting mitochondrial fission and STING/p65 signaling
نویسندگان
چکیده
منابع مشابه
Inhibiting mitochondrial fission protects the heart against ischemia/reperfusion injury.
BACKGROUND Whether alterations in mitochondrial morphology affect the susceptibility of the heart to ischemia/reperfusion injury is unknown. We hypothesized that modulating mitochondrial morphology protects the heart against ischemia/reperfusion injury. METHODS AND RESULTS In response to ischemia, mitochondria in HL-1 cells (a cardiac-derived cell line) undergo fragmentation, a process that i...
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ژورنال
عنوان ژورنال: International Journal of Biological Sciences
سال: 2023
ISSN: ['1449-2288']
DOI: https://doi.org/10.7150/ijbs.84426